The Muscular Dystrophies: From Genes to Therapies.

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  • Additional Information
    • Author-Supplied Keywords:
      Muscular dystrophy
      Skeletal muscle
    • NAICS/Industry Codes:
      325414 Biological Product (except Diagnostic) Manufacturing
    • Abstract:
      The genetic basis of many muscular disorders, including many of the more common muscular dystrophies, is now known. Clinically, the recent genetic advances have improved diagnostic capabilities, but they have not yet provided clues about treatment or management. Thanks to better management strategies and therapeutic interventions, however, many patients with a muscular dystrophy are more active and are living longer. Physical therapists, therefore, are more likely to see a patient with a muscular dystrophy, so understanding these muscle disorders and their management is essential. Physical therapy offers the most promise in caring for the majority of patients with these conditions, because it is unlikely that advances in gene therapy will significantly alter their clinical treatment in the near future. This perspective covers some of the basic molecular biological advances together with the clinical manifestations of the muscular dystrophies and the latest approaches to their management. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of Physical Therapy is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
    • Author Affiliations:
      1Research Associate, Department of Physiology, University of Maryland, School of Medicine, 685 W Baltimore St, Baltimore, MD 21201 (USA)
      2Assistant Professor, Department of Neurology, University of Maryland, School of Medicine
      3Professor, Department of Physiology, University of Maryland, School of Medicine
    • ISSN:
      0031-9023
    • Accession Number:
      19426840
  • Citations
    • ABNT:
      LOVERING, R. M.; PORTER, N. C.; BLOCH, R. J. The Muscular Dystrophies: From Genes to Therapies. Physical Therapy, [s. l.], v. 85, n. 12, p. 1372–1388, 2005. Disponível em: . Acesso em: 25 ago. 2019.
    • AMA:
      Lovering RM, Porter NC, Bloch RJ. The Muscular Dystrophies: From Genes to Therapies. Physical Therapy. 2005;85(12):1372-1388. http://ezproxy.parker.edu/login?url={targeturl}. Accessed August 25, 2019.
    • APA:
      Lovering, R. M., Porter, N. C., & Bloch, R. J. (2005). The Muscular Dystrophies: From Genes to Therapies. Physical Therapy, 85(12), 1372–1388. Retrieved from http://ezproxy.parker.edu/login?url={targeturl}
    • Chicago/Turabian: Author-Date:
      Lovering, Richard M., Neil C. Porter, and Robert J. Bloch. 2005. “The Muscular Dystrophies: From Genes to Therapies.” Physical Therapy 85 (12): 1372–88. http://ezproxy.parker.edu/login?url={targeturl}.
    • Harvard:
      Lovering, R. M., Porter, N. C. and Bloch, R. J. (2005) ‘The Muscular Dystrophies: From Genes to Therapies’, Physical Therapy, 85(12), pp. 1372–1388. Available at: http://ezproxy.parker.edu/login?url={targeturl} (Accessed: 25 August 2019).
    • Harvard: Australian:
      Lovering, RM, Porter, NC & Bloch, RJ 2005, ‘The Muscular Dystrophies: From Genes to Therapies’, Physical Therapy, vol. 85, no. 12, pp. 1372–1388, viewed 25 August 2019, .
    • MLA:
      Lovering, Richard M., et al. “The Muscular Dystrophies: From Genes to Therapies.” Physical Therapy, vol. 85, no. 12, Dec. 2005, pp. 1372–1388. EBSCOhost, ezproxy.parker.edu/login?url={targeturl}.
    • Chicago/Turabian: Humanities:
      Lovering, Richard M., Neil C. Porter, and Robert J. Bloch. “The Muscular Dystrophies: From Genes to Therapies.” Physical Therapy 85, no. 12 (December 2005): 1372–88. http://ezproxy.parker.edu/login?url={targeturl}.
    • Vancouver/ICMJE:
      Lovering RM, Porter NC, Bloch RJ. The Muscular Dystrophies: From Genes to Therapies. Physical Therapy [Internet]. 2005 Dec [cited 2019 Aug 25];85(12):1372–88. Available from: http://ezproxy.parker.edu/login?url={targeturl}