Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein.

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  • Additional Information
    • Author-Supplied Keywords:
      base excision repair
      DNA glycosylase
      gene targeting
      Neil3
    • NAICS/Industry Codes:
      112990 All Other Animal Production
    • Abstract:
      We cloned cDNA and genomic DNA containing exon 1 of mouse Neil3. Neil3 spans 52.4 kb and consists of 10 exons. Northern blot analysis revealed that Neil3 mRNA was selectively expressed in thymus, spleen and bone marrow. High levels of Neil3 mRNA were also detected in various mouse B cell lines by RT-PCR. Immunofluorescence microscopy using anti-NEIL3 revealed that recombinant mouse NEIL3 is localized in the nuclei. In mouse splenocytes, the level of Neil3 mRNA significantly increased after mitogen stimulation in vitro. We established NEIL3-null mice, which are viable and fertile. We found candidate sequences for NEIL3 orthologues in a DNA database from dog and zebrafish in addition to human and mouse, but not invertebrates. NEIL3 may function exclusively in vertebrates, such as mammals. [ABSTRACT FROM PUBLISHER]
    • Abstract:
      Copyright of Journal of Biochemistry is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
    • Author Affiliations:
      1Division of Neurofunctional Genomics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka 812-8582.
    • ISSN:
      0021-924X
    • Accession Number:
      10.1093/jb/mvi168
    • Accession Number:
      44543738
  • Citations
    • ABNT:
      TORISU, K. et al. Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein. Journal of Biochemistry, [s. l.], v. 138, n. 6, p. 763–772, 2005. Disponível em: . Acesso em: 20 nov. 2019.
    • AMA:
      Torisu K, Tsuchimoto D, Ohnishi Y, Nakabeppu Y. Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein. Journal of Biochemistry. 2005;138(6):763-772. doi:10.1093/jb/mvi168.
    • APA:
      Torisu, K., Tsuchimoto, D., Ohnishi, Y., & Nakabeppu, Y. (2005). Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein. Journal of Biochemistry, 138(6), 763–772. https://doi.org/10.1093/jb/mvi168
    • Chicago/Turabian: Author-Date:
      Torisu, Kumiko, Daisuke Tsuchimoto, Yoshinori Ohnishi, and Yusaku Nakabeppu. 2005. “Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein.” Journal of Biochemistry 138 (6): 763–72. doi:10.1093/jb/mvi168.
    • Harvard:
      Torisu, K. et al. (2005) ‘Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein’, Journal of Biochemistry, 138(6), pp. 763–772. doi: 10.1093/jb/mvi168.
    • Harvard: Australian:
      Torisu, K, Tsuchimoto, D, Ohnishi, Y & Nakabeppu, Y 2005, ‘Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein’, Journal of Biochemistry, vol. 138, no. 6, pp. 763–772, viewed 20 November 2019, .
    • MLA:
      Torisu, Kumiko, et al. “Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein.” Journal of Biochemistry, vol. 138, no. 6, Dec. 2005, pp. 763–772. EBSCOhost, doi:10.1093/jb/mvi168.
    • Chicago/Turabian: Humanities:
      Torisu, Kumiko, Daisuke Tsuchimoto, Yoshinori Ohnishi, and Yusaku Nakabeppu. “Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein.” Journal of Biochemistry 138, no. 6 (December 2005): 763–72. doi:10.1093/jb/mvi168.
    • Vancouver/ICMJE:
      Torisu K, Tsuchimoto D, Ohnishi Y, Nakabeppu Y. Hematopoietic Tissue–Specific Expression of Mouse Neil3 for Endonuclease VIII–Like Protein. Journal of Biochemistry [Internet]. 2005 Dec [cited 2019 Nov 20];138(6):763–72. Available from: http://widgets.ebscohost.com/prod/customlink/proxify/proxify.php?count=1&encode=0&proxy=&find_1=&replace_1=&target=http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=a9h&AN=44543738&authtype=sso&custid=s5834912