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Proteostasis and Proteolysis

• Authors : Niki Chondrogianni; Elah Pick; Anna Gioran

Subjects: Proteins; Proteomics; Proteolytic enzymesSCIENCE / Life Sciences / Molecular Biology; MEDICAL / Biochemistry; SCIENCE / Chemistry / Organic

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Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation.

• Authors : Yamanaka S; Division of Cell-Free Sciences, Proteo-Science Center, Ehime University, Matsuyama, 790-8577, Japan.; Division of Proteo-Interactome, Proteo-Science Center, Ehime University, Matsuyama, 790-8577, Japan.

• Source: Nature communications [Nat Commun] 2023 Aug 18; Vol. 14 (1), pp. 4683. Date of Electronic Publication: 2023 Aug 18.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Mathematical Model for Covalent Proteolysis Targeting Chimeras: Thermodynamics and Kinetics Underlying Catalytic Efficiency.

• Authors : Chaudhry C; Molecular & Cellular Pharmacology, Lead Discovery, Janssen Research and Development, LLC, Spring House, Pennsylvania 19477, United States.

• Source: Journal of medicinal chemistry [J Med Chem] 2023 May 11; Vol. 66 (9), pp. 6239-6250. Date of Electronic Publication: 2023 Apr 26.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Crizotinib-based proteolysis targeting chimera suppresses gastric cancer by promoting MET degradation.

• Authors : Chen JJ; Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China.

• Source: Cancer science [Cancer Sci] 2023 May; Vol. 114 (5), pp. 1958-1971. Date of Electronic Publication: 2023 Feb 07.Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic

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THE FEATURES OF LIMITED PROTEOLYSIS IN PLACENTAL FIBRINOID IN COMBINATION WITH INFLAMMATION AND IRON DEFICIENCY ANEMIA OF PREGNANT WOMEN.

• Authors : Ilika VV; BUKOVINIAN STATE MEDICAL UNIVERSITY, CHERNIVTSI, UKRAINE.; Garvasiuk OV

• Source: Wiadomosci lekarskie (Warsaw, Poland : 1960) [Wiad Lek] 2023; Vol. 76 (5 pt 1), pp. 1022-1028.Publisher: Aluna Publishing Country of Publication: Poland NLM ID: 9705467 Publication Model: Print Cited Medium: Print ISSN: 0043-5147 (Print)

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Comprehensive Transcriptomic Analysis of Novel Class I HDAC Proteolysis Targeting Chimeras (PROTACs).

• Authors : Baker IM; Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 7RH, U.K.; Smalley JP

• Source: Biochemistry [Biochemistry] 2023 Feb 07; Vol. 62 (3), pp. 645-656. Date of Electronic Publication: 2022 Aug 10.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet

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Drug delivery challenges and formulation aspects of proteolysis targeting chimera (PROTACs).

• Authors : Saraswat AL; College of Pharmacy and Health Sciences, St John's University, Queens, NY 11439, USA.; Vartak R

• Source: Drug discovery today [Drug Discov Today] 2023 Jan; Vol. 28 (1), pp. 103387. Date of Electronic Publication: 2022 Sep 29.Publisher: Elsevier Science Ltd. Country of Publication: England NLM ID: 9604391 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Targeting of SOS1: from SOS1 Activators to Proteolysis Targeting Chimeras.

• Authors : Hamilton G; Institute of Pharmacology, Medical University of Vienna, Vienna, A-1090, Austria.; Stickler S

• Source: Current pharmaceutical design [Curr Pharm Des] 2023; Vol. 29 (22), pp. 1741-1746.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9602487 Publication Model: Print Cited Medium: Internet

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Permissive Conformations of a Transmembrane Helix Allow Intramembrane Proteolysis by γ-Secretase.

• Authors : Ortner M; Chair of Biopolymer Chemistry, Technical University of Munich, Freising, Germany.; Guschtschin-Schmidt N

• Source: Journal of molecular biology [J Mol Biol] 2023 Sep 15; Vol. 435 (18), pp. 168218. Date of Electronic Publication: 2023 Aug 01.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Design, Synthesis and Biological Evaluation of α-Synuclein Proteolysis-Targeting Chimeras.

• Authors : Wen T; School of Chemistry, Sun Yat-sen University, Guangzhou 510006, China.; Chen J

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 May 31; Vol. 28 (11). Date of Electronic Publication: 2023 May 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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